解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Continuous surveillance of influenza was carried out in Pune between 1978 and 1990. Most of the cases were identified during investigation of 16 outbreaks of influenza in Pune over this period. The majority of cases were children. Ten of the outbreaks occurred during rainy seasons. A total of 290 isolates consisting o...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::A follow-up study of coronary heart disease (CHD) was carried out among adults in Delhi 3 years after an initial community-based epidemiological survey of the same population. A total of 575 of the 814 cases of CHD detected clinically and by electrocardiogram (ECG) in the initial survey took part. On re-examination of...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::The recommended procedures and criteria for T-cell receptor (TCR) designations are described. The officially adopted designations are for the TCR A, B, D and G loci and for V, D, J and C segments. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::This article provides an overview of the current Chinese health care system with particular emphasis on rural-urban differences. China's post-1978 economic reforms, although they improved general living standards, created some unintended consequences, as evidenced by the disintegration of the rural cooperative medical...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract::Highly sensitive case definitions were first introduced by national poliomyelitis eradication programmes to avoid missing true cases of the disease, though false-positive diagnostic errors could still occur owing to low specificity. Extensive data from all 1620 cases of acute, flaccid paralysis reported in Brazil duri...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A serological survey was conducted among Tuareg nomads to determine their level of immunity to measles. More than half (57.9%) of the children under 10 years of age did not have detectable antibodies to measles, suggesting that transmission of the disease is low in this mobile population. Mothers' reports of their chi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Early identification of children at high risk of diarrhoea-associated dehydration would be of great value to health care workers in developing countries. To identify prognostic factors for life-threatening dehydration, we carried out a case-control study among under-2-year-olds in Porto Alegre, Brazil. Cases were 192 ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The transmissible spongiform encephalopathies (TSE) include bovine spongiform encephalopathy (BSE), which was first described in 1986 in the United Kingdom but has occurred subsequently in several other countries. This Memorandum reviews the existing state of knowledge on all the known spongiform encephalopathies, and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Handicap is the result of a process of disablement whose origin is a pathological condition (disease). According to some definitions of health (e.g., a state of complete physical, mental and social well-being), the classical biomedical concept is too restrictive to cover all the consequences of disease. New models hav...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Selective population chemotherapy using a single dose of praziquantel (40 mg per kg body weight), which was offered to 29,365 schoolchildren in Abu El Matameer and 40,241 in Abo Homos districts, Beheira governorate in the Nile delta, reduced the prevalence of schistosomiasis from 75.4% to 40.9% (reduction of 45.8%) an...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Described are the results of an international collaborative study to evaluate the use of whole blood samples spotted on filter-paper (BSP) for the detection of antibodies to human immunodeficiency virus type 1 (HIV-1). BSP samples were collected from 40 patients at risk for HIV-1 infection and tested blindly using com...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::An epidemic of sleeping sickness, which started in 1976 in a focus within the county of Luuka in Central Busoga, has spread to cover the three districts of Busoga and large parts of the neighbouring districts of Tororo and Mukono. Forty-three isolates of the subgenus Trypanozoon from Busoga and Tororo (27 from man, 9 ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Chloroquine-resistant Plasmodium falciparum has been spreading rapidly after its emergence in 1988 in Yekepa. The in vivo and in vitro susceptibilities to quinine and quinidine, compared to chloroquine, were studied by investigating the number of treatment days required for radical cure and estimating the quinine conc...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract::Manpower projections for oral health are generally held to be more accurate than those for other health sectors since the diseases involved and their treatment times can be predicted more precisely. Nevertheless most oral health manpower projections are either overestimates or are not in line with the resources of ind...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::In March 1990 a study was carried out in the village of Kicheba, United Republic of Tanzania, in which the pyrethroid insecticide lambda-cyhalothrin was sprayed on all the internal surfaces of houses and other shelters at a coverage of about 25 mg of active ingredient per m2. Every day for 6 days, 12 spraymen and 3 sq...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The operational and diagnostic performance of a two-step method for the cost-effective screening of urinary schistosomiasis was investigated in the Kilosa District of east-central Tanzania. In the first step a simple questionnaire was administered to 15,073 primary schoolchildren by their class teachers over a 4-week ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The efficacy of standard potency Edmonston-Zagreb (E-Z) measles vaccine was tested in a randomized trial of Black infants in a rural area of South Africa where a measles epidemic was occurring. The following immunization schedules were used: 48 infants aged 4-8.5 months who received 3.9 log 50 infectious units of E-Z ...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract::This paper describes the research conducted by a WHO collaborative study group for the development of a questionnaire method for the assessment of quality in child-care settings. The results of an inter-rater reliability study undertaken in Greece and Nigeria suggest that the Child Care Facility Schedule (CCFS), compo...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::On the basis of geoclimatic characteristics, the Saharan region of Algeria (area, 2 million km2) is made up of several subregions; analysis of the historical data on malaria in this region seems to show that the epidemiological situation is closely linked to climatic and hydrographic conditions. A longitudinal sero-ep...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::To assess its potential applications in plague surveillance and control programmes, an enzyme-linked immunosorbent assay (ELISA) that captures the specific Yersinia pestis F1 antigen was used to determine the amounts of this antigen present in samples of blood and spleens from laboratory rats with acute plague, in the...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Sexually transmitted diseases (STD) are now the commonest group of notifiable infectious diseases in most countries, particularly in the age group of 15 to 50 years and in infants. Their control is important considering the high incidence of acute infections, complications and sequelae, their socioeconomic impact, and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological examinations of the lesions indicated that 788 individuals (35.7%) were also infected with one or more path...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Recombinant proteins directed against the circumsporozoite (CS) protein of Plasmodium vivax were tested for safety, immunogenicity, and efficacy in Saimiri sciureus boliviensis monkeys. The monkeys were immunized 3 times with either alum or muramyl tripeptide as adjuvant, and were challenged with 10,000 sporozoites (P...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Monoclonal antibody NYS4 recognizes a single 140 kDa antigen on the surface of Plasmodium yoelii sporozoites, an antigen which is distinct from the extensively characterized circumsporozoite (CS) protein. To more thoroughly characterize this additional surface component, a genomic expression library was screened with ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The source (species of origin), type, and subgroup (where applicable) of the immunoglobulin chain are indicated prior to the numbers of the first and last amino acid residues comprising the synthesized sequence (stated in parentheses), e.g., human gamma 1 (289-298) or rat epsilon (143-147). Square brackets indicate th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::This Memorandum summarizes current knowledge on the epidemiology of cholera and diarrhoea due to enterotoxigenic Escherichia coli (ETEC) and outlines the results of recent research to develop an effective oral vaccine against cholera. The meeting reviewed current research on the protective antigens of ETEC and made a ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::When mice are immunized with radiation-attenuated sporozoites they are solidly protected against sporozoite challenge by an immune response that has been shown to require CD8+ lymphocytes in several strains of mice. The target of this CD8+ T-cell-dependent immunity has not been established. Immune BALB/c mice were sho...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The distribution and epidemiology of parasitic diseases in both urban and periurban areas of endemic countries have been changing as development progresses. The following different scenarios involving Chagas disease, lymphatic filariasis, leishmaniasis and schistosomiasis are discussed: (1) infected persons entering n...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::As a result of improved medical services and diagnosis of cystic fibrosis (CF), it has in recent years become clear that this is a common genetic disorder with a worldwide distribution. The average life expectancy of CF patients is very low in the developing world, but in developed countries this fatal childhood disea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Reported is the use of a simplified methodology for carrying out a community-based epidemiological assessment that is compatible with the goals of primary health care research. For this purpose, a current-status life table analysis of data from 1131 women who were served by community health workers in the State of Méx...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The frequency of radiological examinations in a country is an important indicator of the general scope of such services in that setting. Frequency data obtained from surveys provide health planners with valuable information that can form an objective basis for resource allocation. Also, from the point of view of radia...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The evaluation of nutritional status using anthropometry has been widely employed in field studies and nutritional surveillance programmes. Two of the primary indicators used, weight-for-age and height-for-age, require accurate age information for proper assessments to be made. Three data sets on nutritional status we...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Termination of early pregnancy by vacuum aspiration is a well-established technique. The procedure is highly effective and has a low complication rate, particularly when performed during the first few weeks after missed menses. However, this parasurgical method requires skilled health care personnel, and attempts have...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract::The usefulness of a recently developed portable haemoglobinometer in primary health care was assessed in a survey of anaemia carried out in an isolated Indian community living in the jungles of northern Peru. This haemoglobinometer requires only one drop of blood to be added to a disposable cuvette without predilution...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The treatment received by children aged under 5 years with diarrhoea was studied in the Hospital Infantil de México (Federico Goméz), Mexico City. The costs of treatment were calculated and estimates were made of how these had changed since the establishment of an oral rehydration unit in the hospital in 1985. The res...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::From the standpoint of nutritional needs, physiological maturation, and immunological safety the provision of foods other than breast milk before about four months of age is unnecessary and may also be harmful. On the other hand, many infants require some complementary feeding by about six months of age. There are a n...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Village-wide use of permethrin-impregnated bed nets, compared with placebo-treated nets, has reduced clinical attacks of malaria by 63% in the Gambia. Costs were calculated for nets made by local tailors and for their treatment with insecticide in the villages, as well as for targeted chemoprophylaxis and back-up trea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The efficacy of BCG vaccine in preventing the clinical manifestations of leprosy in a tuberculosis-free area of Papua New Guinea is reported. Between 1963 and 1966 a total of 5356 subjects, randomized to receive BCG or saline inoculations, were examined for leprosy before the vaccination and surveillance was continued...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-01-01 00:00:00
abstract::A taxonomic approach using cluster analysis and principal component analysis has grouped the countries of the world in eight clusters, in an initial attempt to propose a worldwide spatial classification based on the following health-related indicators: (a) those directly related to the health status of the population;...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Hepatic damage caused by chronic exposure to arsenic has been frequently described. Here we report on 13 patients from West Bengal, India, who consumed large amounts of arsenic in drinking water. An epidemiological investigation of the study area showed evidence of chronic arsenical dermatosis and hepatomegaly in 62 (...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00